Don't know much about it, but I don't know alot about many things
Bus length issues?
Thoughts
Could use 28 segment LED driver/GPIO chip to handle 12 port switching module with 12 lines for driving relays and 12 lines for sensing toggle buttons for manual overriding of relay state.
Could build a simple module to control AZ/EL rotors using I2C 10 or 12 bit A-D converters. Relays could be driven by six bit GPIO chips.